Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.350 | GeneticVariation | disease | BEFREE | The genetic polymorphism in dopamine β-hydroxylase is associated with methamphetamine-induced paranoia and influences smoking initiation. | 24521142 | 2014 | ||||
|
0.350 | GeneticVariation | disease | BEFREE | A single nucleotide polymorphism (SNP; C-1021T) in the DbetaH gene is relevant to paranoia associated with disulfiram pharmacotherapy for cocaine addiction. | 19462300 | 2009 | ||||
|
0.350 | GeneticVariation | disease | BEFREE | Dopamine beta-hydroxylase gene (DbetaH) -1021C-->T influences self-reported paranoia during cocaine self-administration. | 17157269 | 2007 | ||||
|
0.350 | Biomarker | disease | CTD_human | Dopamine beta-hydroxylase gene (DbetaH) -1021C-->T influences self-reported paranoia during cocaine self-administration. | 17157269 | 2007 | ||||
|
0.350 | Biomarker | disease | CTD_human | Recently, two polymorphisms (DBH5'-Ins/del and DBH 444 g/a) of the Dopamine Beta Hydroxylase (DBH) gene were isolated, and one haplotype (Del-a) was found to be associated with low DBH activity and cocaine-induced paranoia. | 12555232 | 2003 | ||||
|
0.350 | AlteredExpression | disease | BEFREE | Recently, two polymorphisms (DBH5'-Ins/del and DBH 444 g/a) of the Dopamine Beta Hydroxylase (DBH) gene were isolated, and one haplotype (Del-a) was found to be associated with low DBH activity and cocaine-induced paranoia. | 12555232 | 2003 | ||||
|
0.350 | Biomarker | disease | CTD_human | As predicted, the low-DbetaH-associated haplotype, Del-a, was significantly more frequent (P = 0.0003) in subjects endorsing cocaine-induced paranoia (n = 29) than in those denying it (n = 16). | 10673769 | 2000 | ||||
|
0.350 | Biomarker | disease | BEFREE | We then estimated DBH haplotype frequencies in cocaine-dependent European Americans rated for cocaine-induced paranoia (n = 45). | 10673769 | 2000 |