In this study, we have newly identified a haplotype-tagging SNP, rs225396, in ABCG1 to be associated with PCV and nAMD in Chinese and Japanese cohorts.
We found that in Asian population, CETP rs3764261 (T allele; OR = 1.46; 95% CI: 1.28-1.665, <i>P</i> < 0.01), CETP rs2303790 (G allele; OR = 1.57; 95% CI: 1.258-1.96, <i>P</i> < 0.01), and ABCG1rs57137919 (A allele; OR = 1.168; 95% CI: 1.016-1.343, <i>P</i> < 0.01) were significantly associated with PCV, and ABCG1rs57137919 (A allele; OR = 1.208, 95% CI: 1.035-1.411, <i>P</i> < 0.01) has different effects in PCV and AMD.