Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.030 Biomarker disease BEFREE Dual targeting BTK and BCL2 with ibrutinib and venetoclax has improved outcomes in MCL patients who were predicted not to respond to conventional therapy, but it is unlikely to be curative. 30791947 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.030 AlteredExpression disease BEFREE MCL samples expressing high levels of Bcl-2 and high Bcl-2/Bax ratios tend to be less effective to ZGDHu-1. 28035065 2017
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.030 Biomarker disease BEFREE These results suggest co-targeting of BTK and BCL2 as a new therapeutic strategy in MCL, especially for patients with primary resistance to ibrutinib. 27157620 2016