DisGeNET - a database of gene-disease associations

Pseudohyperkalemia Cardiff, C1861453

Gene: HLA-C ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Score _gda

Association Type

Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	3107
Gene Symbol:	HLA-C

HLA-C

0.030

Biomarker

disease

BEFREE

Our results indicated that HLA-C*08:01 was a risk factor for CHC, while HLA-C*08:04 and HLA-B*13:01 were protective factors against CHC.

30932338

2019

Entrez Id:	3107
Gene Symbol:	HLA-C

HLA-C

0.030

Biomarker

disease

BEFREE

In conclusion, HLA-C(*)15 is an important host immunogenetic factor with an inverse association to HCV viral load in CHC patients in Taiwan.

23628398

2013

Entrez Id:	3107
Gene Symbol:	HLA-C

HLA-C

0.030

GeneticVariation

disease

BEFREE

We genotyped chronic hepatitis C (CHC) genotype 1 patients with PegIFN/R treatment-induced clearance (n = 417) and treatment failure (n = 493), and 234 individuals with spontaneous clearance, for HLA-C C1 versus C2, presence of inhibitory and activating KIR genes, and two IL28B SNPs, rs8099917 and rs12979860.

21931540

2011