×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
Biomarker
disease
CTD_human
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
Biomarker
disease
MGD
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
A low prevalence of sarcomeric gene variants in a Chinese cohort with left ventricular non-compaction.
24691700
2015
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
GeneticVariation
disease
UNIPROT
A new mutation of the cardiac troponin T gene causing familial hypertrophic cardiomyopathy without left ventricular hypertrophy.
10525521
1999
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
A new mutation of the cardiac troponin T gene causing familial hypertrophic cardiomyopathy without left ventricular hypertrophy.
10525521
1999
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
A novel arginine to tryptophan (R144W) mutation in troponin T (cTnT) gene in an indian multigenerational family with dilated cardiomyopathy (FDCM).
24992688
2014
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
GeneticVariation
disease
UNIPROT
A rapid protocol for cardiac troponin T gene mutation detection in familial hypertrophic cardiomyopathy.
9482583
1998
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
A systematic approach to assessing the clinical significance of genetic variants.
24033266
2013
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Allosteric effects of cardiac troponin TNT1 mutations on actomyosin binding: a novel pathogenic mechanism for hypertrophic cardiomyopathy.
24480310
2014
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
GeneticVariation
disease
UNIPROT
Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere.
8205619
1994
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere.
8205619
1994
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
GeneticVariation
disease
CLINVAR
Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere.
8205619
1994
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Alterations in thin filament regulation induced by a human cardiac troponin T mutant that causes dilated cardiomyopathy are distinct from those induced by troponin T mutants that cause hypertrophic cardiomyopathy.
12186860
2002
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Altered regulation of cardiac muscle contraction by troponin T mutations that cause familial hypertrophic cardiomyopathy.
10617660
2000
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Analysis of the molecular pathogenesis of cardiomyopathy-causing cTnT mutants I79N, ΔE96, and ΔK210.
23663841
2013
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Ca(2+) activation of myofilaments from transgenic mouse hearts expressing R92Q mutant cardiac troponin T.
11158969
2001
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Ca(2+)-desensitizing effect of a deletion mutation Delta K210 in cardiac troponin T that causes familial dilated cardiomyopathy.
11773635
2002
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Ca2+ sensitization and potentiation of the maximum level of myofibrillar ATPase activity caused by mutations of troponin T found in familial hypertrophic cardiomyopathy.
10085122
1999
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Cardiac troponin T mutation in familial cardiomyopathy with variable remodeling and restrictive physiology.
18651846
2008
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Cardiac troponin T mutation R141W found in dilated cardiomyopathy stabilizes the troponin T-tropomyosin interaction and causes a Ca2+ desensitization.
14654368
2003
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy.
10449439
1999
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Cardiomyopathy-causing deletion K210 in cardiac troponin T alters phosphorylation propensity of sarcomeric proteins.
20079745
2010
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Changes in the chemical and dynamic properties of cardiac troponin T cause discrete cardiomyopathies in transgenic mice.
16326803
2005
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Characterization of a phenotype-based genetic test prediction score for unrelated patients with hypertrophic cardiomyopathy.
24793961
2014
×
Entrez Id:
7139
Gene Symbol:
TNNT2
TNNT2
0.900
CausalMutation
disease
CLINVAR
Characterization of the two eIF4A-binding sites on human eIF4G-1.
11060291
2001