Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.400 | GeneticVariation | disease | BEFREE | Estrogen receptor alpha (ESR1) gene variation is associated with a range of important estrogen-dependent characteristics, including responses of lipid profile and atherosclerotic severity to hormone replacement therapy, coronary heart disease risk, and migraine. | 16179580 | 2005 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | Qualitative assessment of previous evidence and an updated meta-analysis confirms lack of association between the ESR1 rs2234693 (PvuII) variant and coronary heart disease in men and women. | 19608186 | 2009 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | Gender-specific effect of estrogen receptor-1 gene polymorphisms in coronary artery disease and its angiographic severity in Chinese population. | 18582450 | 2008 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | The (TA)(n)length in the ER-alpha gene promoter region is associated with the angiographic severity of CAD in young patients. | 14972425 | 2004 | ||||
|
0.400 | Biomarker | disease | CTD_human | Modulation of gene expression by Polyalthia longifolia in postmenopausal women with coronary artery disease: an in vitro study. | 20559769 | 2010 | ||||
|
0.400 | Biomarker | disease | CTD_human | Premature coronary artery disease associated with a disruptive mutation in the estrogen receptor gene in a man. | 9396482 | 1997 | ||||
|
0.400 | GeneticVariation | disease | LHGDN | The relationship of the ESR1 gene polymorphisms with the presence of coronary artery disease determined by coronary angiography. | 18294052 | 2007 | ||||
|
0.400 | GeneticVariation | disease | LHGDN | This study seeks to investigate the association between the ESR1 haplotype created by the c.454-397 T>C and c.454-351 A>G polymorphisms, the length of the (TA)n repeats, and the angiographic extent of CAD. | 16159931 | 2005 |