| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | disease | BEFREE | Patients with MI had higher free IGF-1 (p=0.003) and PAPP-A (p=0.011), but lower intact IGFBP-4 (p=0.006) compared with patients with stable CAD or healthy controls. | 30497090 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | Association of IGF-1 with coronary collateral circulation in stable coronary artery disease. | 28685580 | 2017 | ||||
|
0.080 | Biomarker | disease | BEFREE | The Effect of GHR/exon-3 Polymorphism and Serum GH, IGF-1 and IGFBP-3 Levels in Diabetes and Coronary Heart Disease. | 25977383 | 2016 | ||||
|
0.080 | Biomarker | disease | BEFREE | The aim of the present study is to analyze the relationships between functional polymorphisms in genes encoding basic fibroblast growth factor (bFGF, FGF2), epidermal growth factor (EGF), insulin-like growth factor-1 (IGF-1), platelet derived growth factor-B (PDGFB), transforming growth factor-β1 (TGF-β1) and vascular endothelial growth factor A (VEGF-A) and the severity of coronary atherosclerosis in patients with stable CAD undergoing their first coronary angiography. | 27835972 | 2016 | ||||
|
0.080 | Biomarker | disease | BEFREE | In CAD patients, the contributions of IGF-I +1770 and +6093 could be through the effect on blood pressure in CAD patients. | 23423640 | 2013 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Like HDL markers, high levels of IGF-1 confer protection against coronary artery disease. | 21708381 | 2011 | ||||
|
0.080 | Biomarker | disease | BEFREE | The importance of insulin-like growth factor-1 (IGF-1) in coronary artery disease (CAD) due to wide range of its biological effects and its therapeutic potential, has already been described. | 21046444 | 2010 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | By contrast, recent prospective epidemiological studies suggest that relatively higher IGF-I levels may reduce the risk of type 2 diabetes and coronary heart disease. | 15879687 | 2005 |