Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 100
Gene Symbol: ADA
ADA
0.010 GeneticVariation disease BEFREE Dysglycemia was found in 57.7% by ADA criteria [Diabetes in 10.5% and prediabetes in 47.2%]. 29802954 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
0.010 Biomarker disease BEFREE Higher adiponectin and lower orosomucoid were associated with 70 or lower mg/dL of postload glucose, a possible inverse marker for dysglycemia, in young women independently of DXA-derived fat mass and distribution, insulin secretion and IR. 30899529 2019
Entrez Id: 133
Gene Symbol: ADM
ADM
0.010 GeneticVariation disease BEFREE Our study suggests a potential role of genetic variants in the ADM gene in the development of dysglycemia in our local Chinese population. 21075100 2011
Entrez Id: 197
Gene Symbol: AHSG
AHSG
0.010 Biomarker disease BEFREE To evaluate the impact of changes over 2 years in fetuin-A and the liver enzymes alanine aminotransferase (ALT), aspartate aminotransferase (AST), and γ-glutamyltransferase (GGT) on changes in insulin sensitivity, β-cell function, and glycemia in women with varying degrees of previous gestational dysglycemia, reflecting a range of future diabetic risk. 29897453 2018
Entrez Id: 217
Gene Symbol: ALDH2
ALDH2
0.010 GeneticVariation disease BEFREE In contrast, PCSK9, APOB, LPA, CETP, PLG, NPC1L1 and ALDH2 were identified as "druggable" loci that alter LDL-C and risk of CAD without displaying associations with dysglycemia. 26946290 2016
Entrez Id: 27329
Gene Symbol: ANGPTL3
ANGPTL3
0.010 Biomarker disease BEFREE Future trials will reveal if ANGPTL3 inhibition could be considered an alternative therapeutic target for dyslipidemia and dysglycemia. 30944669 2019
Entrez Id: 116519
Gene Symbol: APOA5
APOA5
0.010 GeneticVariation disease BEFREE Associations of apolipoprotein A5 (APOA5), glucokinase (GCK) and glucokinase regulatory protein (GCKR) polymorphisms and lifestyle factors with the risk of dyslipidemia and dysglycemia in Japanese - a cross-sectional data from the J-MICC Study. 22517333 2012
Entrez Id: 348
Gene Symbol: APOE
APOE
0.010 GeneticVariation disease BEFREE Dysglycemia was also associated with lower performance in language, speed and visuospatial function although these associations were attenuated when adjusted for education, APOE-ε4, ethnic group and vascular risk factors. 27917464 2017
Entrez Id: 948
Gene Symbol: CD36
CD36
0.010 AlteredExpression disease BEFREE C3H/HeN, do not develop hepatic steatosis, insulin resistance, or dysglycemia on a sucrose-enriched diet, suggesting that elevated insulin levels, via enhanced CD36 expression, provoke fatty liver development that in turn leads to hepatic insulin resistance and dysglycemia. 26085100 2015
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.010 AlteredExpression disease BEFREE Therefore we assessed the levels of C-reactive protein (CRP) and Interleukin 6 (IL-6) on a cohort of PLHIV and its associations with dysglycemia in Tanzania. 31331321 2019
Entrez Id: 1803
Gene Symbol: DPP4
DPP4
0.010 AlteredExpression disease BEFREE The combination add-on therapy of insulin glargine, on metformin and DPP-4 inhibitors with or without SU was safe and efficient in reducing HbA1c levels and thus, is a preferable option in managing T2DM patients exhibiting dysglycemia despite the use of OADs. 31237133 2019
Entrez Id: 84467
Gene Symbol: FBN3
FBN3
0.010 GeneticVariation disease BEFREE We compared maternal and paternal contributions to heritability of fasting dysglycemia and to transmission of the PCOS susceptibility allele of D19S884 within the fibrillin-3 gene (D19S884-A8) on fasting dysglycemia. 24878041 2014
Entrez Id: 2641
Gene Symbol: GCG
GCG
0.020 Biomarker disease BEFREE Thus, subjects with RHI displayed both higher postprandial serum GLP-1 and glucagon than the participants with RLI, suggesting that glucagon could play a role in the advent of dysglycemia by insulin resistance. 31759769 2019
Entrez Id: 2641
Gene Symbol: GCG
GCG
0.020 Biomarker disease BEFREE Effects of boschnaloside from Boschniakia rossica on dysglycemia and islet dysfunction in severely diabetic mice through modulating the action of glucagon-like peptide-1. 31102890 2019
Entrez Id: 2645
Gene Symbol: GCK
GCK
0.010 GeneticVariation disease BEFREE Associations of apolipoprotein A5 (APOA5), glucokinase (GCK) and glucokinase regulatory protein (GCKR) polymorphisms and lifestyle factors with the risk of dyslipidemia and dysglycemia in Japanese - a cross-sectional data from the J-MICC Study. 22517333 2012
Entrez Id: 2646
Gene Symbol: GCKR
GCKR
0.010 GeneticVariation disease BEFREE Associations of apolipoprotein A5 (APOA5), glucokinase (GCK) and glucokinase regulatory protein (GCKR) polymorphisms and lifestyle factors with the risk of dyslipidemia and dysglycemia in Japanese - a cross-sectional data from the J-MICC Study. 22517333 2012
Entrez Id: 9518
Gene Symbol: GDF15
GDF15
0.010 Biomarker disease BEFREE GDF15 levels are a biomarker for the use of metformin in people with dysglycemia, and its concentration reflects the dose of metformin. 27974345 2017
Entrez Id: 2875
Gene Symbol: GPT
GPT
0.020 Biomarker disease BEFREE Adult CF men with higher ALT show an increased frequency of dysglycemia and de novo CFRD, lower insulin sensitivity and higher eight. 31318914 2019
Entrez Id: 2875
Gene Symbol: GPT
GPT
0.020 Biomarker disease BEFREE To evaluate the impact of changes over 2 years in fetuin-A and the liver enzymes alanine aminotransferase (ALT), aspartate aminotransferase (AST), and γ-glutamyltransferase (GGT) on changes in insulin sensitivity, β-cell function, and glycemia in women with varying degrees of previous gestational dysglycemia, reflecting a range of future diabetic risk. 29897453 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.010 Biomarker disease BEFREE Therefore we assessed the levels of C-reactive protein (CRP) and Interleukin 6 (IL-6) on a cohort of PLHIV and its associations with dysglycemia in Tanzania. 31331321 2019
Entrez Id: 3630
Gene Symbol: INS
INS
0.010 AlteredExpression disease BEFREE Fathers had higher fasting glucose levels, prevalence of fasting dysglycemia and proinsulin to insulin molar ratios (P < .0001), a marker of defective insulin processing, compared with mothers. 24878041 2014
Entrez Id: 3643
Gene Symbol: INSR
INSR
0.020 Biomarker disease BEFREE Sequencing demonstrated INSR haploinsufficiency accounting for elevated insulin levels and dysglycemia. 19720790 2009
Entrez Id: 3643
Gene Symbol: INSR
INSR
0.020 GeneticVariation disease BEFREE Rabson-Mendenhall syndrome (RMS) is caused by mutations of the insulin receptor and results in extreme insulin resistance and dysglycemia. 23969187 2013
Entrez Id: 3758
Gene Symbol: KCNJ1
KCNJ1
0.010 GeneticVariation disease BEFREE Our findings support that KCNJ1 variation is associated with HCTZ-induced dysglycemia and NOD. 22907731 2013
Entrez Id: 10392
Gene Symbol: NOD1
NOD1
0.010 Biomarker disease BEFREE We hypothesized that Ripk2 was required for Nod1-mediated inflammation, lipolysis and dysglycemia. 28484277 2017