Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.470 | GeneticVariation | disease | BEFREE | Hepatocellular carcinoma and choangiocarcinoma display heterogeneity at both morphologic and molecular levels Cholangiocellular carcinoma is most commonly associated with IDH 1/2 mutations. | 29776636 | 2018 | ||||
|
0.470 | Biomarker | disease | CTD_human | Hepatocellular carcinoma-associated protein markers investigated by MALDI-TOF MS. | 21472284 | 2012 | ||||
|
0.470 | GeneticVariation | disease | BEFREE | Our results for the first time suggest that IDH gene polymorphisms may serve as an independent prognostic marker for HCC patients treated with TACE. | 25355558 | 2014 | ||||
|
0.470 | GeneticVariation | disease | CLINVAR | Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. | 26619011 | 2016 | ||||
|
0.470 | GeneticVariation | disease | BEFREE | Presence of IDH1 mutation was related with poor survival in clear cell HCC patients (P = 0.004). | 28403884 | 2017 | ||||
|
0.470 | Biomarker | disease | BEFREE | Our negative results, together with some previous reports of the absence of IDH1 p.R132 mutations in HCC tissues, suggests that IDH1 p.R132 mutations are not actively involved in the development of HCC. | 24531386 | 2014 | ||||
|
0.470 | Biomarker | disease | BEFREE | Rat liver and hepatoma AS-30D cytosolic fractions exhibited greater Vmax for IDH-1 than for Glc6PDH and 6PGDH whereas human cancer cells and platelets showed greater Vmax for Glc6PDH than for 6PGDH and IDH-1. | 28739529 | 2017 | ||||
|
0.470 | GeneticVariation | disease | BEFREE | K19<sup>+</sup> HCC had TERT promoter mutations less frequently than K19<sup>-</sup> HCC (31% versus 59%; P = 0.022), and lacked alterations in KRAS and IDH1. | 31017316 | 2019 | ||||
|
0.470 | GeneticVariation | disease | BEFREE | In this study, 17 SNPs in seven genes encoding three TCA cycle enzyme families (SDH, FH, and IDH) were genotyped in 492 HCC patients with surgical treatment and their association with overall survival (OS) was analyzed. | 25081338 | 2014 |