Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 Biomarker disease BEFREE DEB-TACE appears to be a feasible treatment for small HCCs. 31646378 2020
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 Biomarker disease BEFREE Patients in DS group can achieve post-transplant survival and HCC recurrence-free probability, at five years, just like patients within MC in patients undergoing DEB-TACE. 31602168 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 Biomarker disease BEFREE Conventional TACE is safe and effective for huge HCCs, but has limited effects in cases with four or more tumors. 30907468 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 Biomarker disease BEFREE <b>Conclusions:</b> Adjuvant TACE does not improve the DFS of HCC patients with tumor size less than 5 cm. 31079496 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 Biomarker disease BEFREE MicroRNA-3163 targets ADAM-17 and enhances the sensitivity of hepatocellular carcinoma cells to molecular targeted agents. 31611551 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 Biomarker disease BEFREE <b>Conclusions</b>: We identified risk factors for extrahepatic progression after TACE in HCC patients. 31598173 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 Biomarker disease BEFREE CalliSpheres Drug-Eluting Bead Transcatheter Arterial Chemoembolization Presents With Better Efficacy and Equal Safety Compared to Conventional TACE in Treating Patients With Hepatocellular Carcinoma. 30862264 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 Biomarker disease BEFREE Retrospective, cohort study of 51 patients treated with DEB-TACE for unresectable HCC was studied: 23 with 100-300 μm particles and 28 with 70-150 μm particles. 31709778 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 GeneticVariation disease BEFREE This study evaluated clinical implications of T cell cytokines and regulatory T cells (Tregs) in HCC patients treated with TACE. 30824840 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 Biomarker disease BEFREE In conclusion, we found that DEB-TACE achieved higher treatment response and prolonged survival compared with cTACE in Chinese HCC patients. 31053181 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 Biomarker disease BEFREE Fifty-eight patients with unresectable HCC and APSs who were treated with DEB-TACE (n=26) or polyvinyl alcohol (PVA) plus TACE (PVA-TACE, n=32) were included in this retrospective study. 30863165 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 Biomarker disease BEFREE Jiedu granule combined with TACE plus GKR is safe in HCC patients with PVTT and this Chinese herbal medicine is worthy to be promoted because of better prognosis which needs further research. 31341898 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 Biomarker disease BEFREE In conclusion, apatinib combined with TACE revealed certain survival benefits for HCC patients who experienced progression following TACE, which can provide a promising strategy for HCC treatment. 30332553 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 Biomarker disease BEFREE To determine the feasibility of pre-TACE IVIM imaging based on histogram analysis for predicting prognosis in the treatment of unresectable hepatocellular carcinoma (HCC). 29922932 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 Biomarker disease BEFREE TACE with degradable starch microspheres (DSM-TACE) as second-line treatment in HCC patients dismissing or ineligible for sorafenib. 30171360 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 Biomarker disease BEFREE Patients with hepatocellular carcinoma waiting for liver transplantation are commonly treated with locoregional treatments, such as TACE and ablation, to prevent tumor progression and dropout and to improve long-term outcome after transplantation. 31185950 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 Biomarker disease BEFREE Tumor response obtained at 1-month CT follow-up for group C was compared with that of control group, composed by 16 matched patients with severe coagulopathy and single HCC < 8 cm, who underwent only TACE in a previous period, performed by the same operator. 31005173 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 Biomarker disease BEFREE Seven well-known HCC staging-systems (including Cancer of the Liver Italian Program-score [CLIP] and Barcelona Clinic liver cancer [BCLC]) and 2 TACE-specific scores (Selection for Transarterial Chemoembolisation Treatment [STATE] and Hepatoma Arterial embolisation Prognostic [HAP]) were rearranged in a cohort of 186 TACE-patients through score-point-analysis and subsequent linking of non-significant adjacent score-points. 30282074 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 GeneticVariation disease BEFREE This was a retrospective review of the first 40 consecutive patients at a UK tertiary hepato-biliary centre, treated for HCC with TACE using radiopaque beads, between May 2017 and March 2019. 31455987 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 Biomarker disease BEFREE This review summarizes the recent advances in the use of DEM-TACE to treat HCC. 30627020 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 Biomarker disease BEFREE The ALPPS is a feasible treatment for HCC patients and it provides a better long-term survival than TACE and it is similar to Resection, less than LT. 31567959 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 GeneticVariation disease BEFREE All included 319 patients who underwent LR for HCC with HVTT, 134 underwent LR alone (the LR group), and 185 patients underwent in adjuvant TACE (the PA-TACE group).PSM matched 107 patients in two groups. 30767178 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 Biomarker disease BEFREE Recently, TACE plus Iodine-125 (125I) seed strand endovascular implantation (ISEI) was shown to be feasible in advanced HCC patients. 31128018 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 GeneticVariation disease BEFREE And subgroup analysis displayed that PFS of patients with largest nodule size >3.3 cm (P = .025) was longer and patients with unilobar disease (P = .009), and patients with no hepatic invasion (P = .019) and Child-pugh stage A (P = .037) had more favorable OS in DEB-TACE+RFA group compared with DEB-TACE group.DEB-TACE+RFA achieved better treatment responses and OS compared with DEB-TACE alone in Chinese HCC patients. 31261491 2019
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
0.100 Biomarker disease BEFREE In this retrospective single-center study, 50 patients with unresectable HCC having undergone DEB-TACE from January 2010 to July 2015 were assessed. 31332502 2019