×
Entrez Id:
1495
Gene Symbol:
CTNNA1
CTNNA1
0.300
Biomarker
disease
CLINGEN
×
Entrez Id:
2956
Gene Symbol:
MSH6
MSH6
0.110
GeneticVariation
disease
CLINVAR
×
Entrez Id:
5892
Gene Symbol:
RAD51D
RAD51D
0.100
GeneticVariation
disease
CLINVAR
×
Entrez Id:
80204
Gene Symbol:
FBXO11
FBXO11
0.100
GeneticVariation
disease
CLINVAR
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
0.100
GeneticVariation
disease
CLINVAR
×
Entrez Id:
2956
Gene Symbol:
MSH6
MSH6
0.110
GeneticVariation
disease
BEFREE
Increasing recognition of the statistical burden posed by HNPCC (5 to 6 percent of all colorectal cancer) mandates that physicians have a better understanding of the genetics, natural history, and distinction between the hereditary site-specific variant (Lynch syndrome I ) and the Cancer Family Syndrome (Lynch syndrome II).
3366037
1988
×
Entrez Id:
2956
Gene Symbol:
MSH6
MSH6
0.110
CausalMutation
disease
CLINVAR
In vivo measurement of the volume of distribution of water in cerebral grey matter: effects on the calculation of regional cerebral blood flow.
1548301
1992
×
Entrez Id:
80204
Gene Symbol:
FBXO11
FBXO11
0.100
CausalMutation
disease
CLINVAR
In vivo measurement of the volume of distribution of water in cerebral grey matter: effects on the calculation of regional cerebral blood flow.
1548301
1992
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
GeneticVariation
disease
UNIPROT
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer.
8261515
1993
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
GeneticVariation
disease
UNIPROT
Mutational analysis of the hMSH2 gene reveals a three base pair deletion in a family predisposed to colorectal cancer development.
7874129
1994
×
Entrez Id:
2052
Gene Symbol:
EPHX1
EPHX1
0.300
Biomarker
disease
CLINGEN
Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants.
7516776
1994
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
Detection of new mutations in six out of 10 Swiss HNPCC families by genomic sequencing of the hMSH2 and hMLH1 genes.
8592341
1995
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
Genetic instability occurs in the majority of young patients with colorectal cancer.
7585065
1995
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
GeneticVariation
disease
UNIPROT
Microsatellite instability and mutation analysis of hMSH2 and hMLH1 in patients with sporadic, familial and hereditary colorectal cancer.
8872463
1996
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
GeneticVariation
disease
UNIPROT
Germline mutations of hMLH1 and hMSH2 genes in Korean hereditary nonpolyposis colorectal cancer.
8797773
1996
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
GeneticVariation
disease
UNIPROT
Microsatellite instability and the role of hMSH2 in sporadic colorectalcancer.
8700523
1996
×
Entrez Id:
4437
Gene Symbol:
MSH3
MSH3
0.300
Biomarker
disease
CLINGEN
hMutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA.
8805365
1996
×
Entrez Id:
4437
Gene Symbol:
MSH3
MSH3
0.300
Biomarker
disease
CLINGEN
hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6.
8942985
1996
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
GeneticVariation
disease
UNIPROT
Hereditary nonpolyposis colorectal cancer (HNPCC): eight novel germline mutations in hMSH2 or hMLH1 genes.
9298827
1997
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
GeneticVariation
disease
UNIPROT
Frequent somatic mutations of hMSH3 with reference to microsatellite instability in hereditary nonpolyposis colorectal cancers.
9240418
1997
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
GeneticVariation
disease
UNIPROT
Use of SSCP analysis to identify germline mutations in HNPCC families fulfilling the Amsterdam criteria.
9048925
1997
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
GeneticVariation
disease
UNIPROT
Identification of concurrent germ-line mutations in hMSH2 and/or hMLH1 in Japanese hereditary nonpolyposis colorectal cancer kindreds.
9419403
1997
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
GeneticVariation
disease
UNIPROT
Hereditary nonpolyposis colorectal cancer families not complying with the Amsterdam criteria show extremely low frequency of mismatch-repair-gene mutations.
9311737
1997
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
CausalMutation
disease
CLINVAR
Systematic analysis of hMSH2 and hMLH1 in young colon cancer patients and controls.
9718327
1998
×
Entrez Id:
4436
Gene Symbol:
MSH2
MSH2
0.600
GeneticVariation
disease
UNIPROT
Novel germline mutations of hMSH2 in a patient with hereditary nonpolyposis colorectal cancer (HNPCC) and in a patient with six primary cancers.
9621522
1998