Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 CausalMutation disease CLINVAR Clinical Actionability of Multigene Panel Testing for Hereditary Breast and Ovarian Cancer Risk Assessment. 26270727 2015
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 CausalMutation disease CLINVAR Patterns and functional implications of rare germline variants across 12 cancer types. 26689913 2015
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 GeneticVariation disease CLINVAR Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart. 26354865 2015
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 GeneticVariation disease UNIPROT Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair. 24141787 2014
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 CausalMutation disease CLINVAR RAD51C--a new human cancer susceptibility gene for sporadic squamous cell carcinoma of the head and neck (HNSCC). 24315737 2014
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 GeneticVariation disease CLINVAR Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair. 24141787 2014
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 CausalMutation disease CLINVAR RAD51C germline mutations found in Spanish site-specific breast cancer and breast-ovarian cancer families. 25086635 2014
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 GeneticVariation disease CLINVAR Pathological features of breast and ovarian cancers in RAD51C germline mutation carriers. 24993905 2014
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 CausalMutation disease CLINVAR Deleterious RAD51C germline mutations rarely predispose to breast and ovarian cancer in Pakistan. 24800917 2014
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 GeneticVariation disease CLINVAR Deleterious RAD51C germline mutations rarely predispose to breast and ovarian cancer in Pakistan. 24800917 2014
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 CausalMutation disease CLINVAR Next-generation sequencing for the diagnosis of hereditary breast and ovarian cancer using genomic capture targeting multiple candidate genes. 24549055 2014
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 GeneticVariation disease CLINVAR Germline mutation in the RAD51B gene confers predisposition to breast cancer. 24139550 2013
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 CausalMutation disease CLINVAR Germline mutation in the RAD51B gene confers predisposition to breast cancer. 24139550 2013
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 CausalMutation disease CLINVAR Germline RAD51C mutations in ovarian cancer susceptibility. 22725699 2013
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 GeneticVariation disease CLINVAR Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: implications for Fanconi anemia and breast cancer susceptibility. 22167183 2012
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 GeneticVariation disease CLINVAR Germline RAD51C mutations confer susceptibility to ovarian cancer. 22538716 2012
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 Biomarker disease CLINGEN Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: implications for Fanconi anemia and breast cancer susceptibility. 22167183 2012
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 GeneticVariation disease CLINVAR Predominance of pathogenic missense variants in the RAD51C gene occurring in breast and ovarian cancer families. 22451500 2012
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 Biomarker disease GENOMICS_ENGLAND Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: implications for Fanconi anemia and breast cancer susceptibility. 22167183 2012
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 CausalMutation disease CLINVAR Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients. 21990120 2012
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 Biomarker disease GENOMICS_ENGLAND Exome sequencing reveals a novel Fanconi group defined by XRCC2 mutation. 22232082 2012
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 GeneticVariation disease CLINVAR Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients. 21990120 2012
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 CausalMutation disease CLINVAR Germline RAD51C mutations confer susceptibility to ovarian cancer. 22538716 2012
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 CausalMutation disease CLINVAR RAD51C is a susceptibility gene for ovarian cancer. 21616938 2011
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.710 CausalMutation disease CLINVAR A HRM-based screening method detects RAD51C germ-line deleterious mutations in Spanish breast and ovarian cancer families. 21537932 2011