HLA-DPB1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Genetic predisposition to JIA is mainly due to HLA class II molecules (HLA-DRB1, HLA-DPB1), although HLA class I molecules and non-HLA genes have been implicated, too.
|
29037901 |
2017 |
HLA-DPB1
|
0.100 |
Biomarker
|
disease |
BEFREE |
HLA DPB1:02:01 has also been associated with oligoarticular and RF-negative polyarticular JIA.
|
26305060 |
2015 |
HLA-DPB1
|
0.100 |
GeneticVariation
|
disease |
LHGDN |
HLA-DRB1, TAP2/TAP1, and HLA-DPB1 haplotypes in Finnish juvenile idiopathic arthritis: more complexity within the MHC.
|
15343265 |
2004 |
HLA-DPB1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
HLA-DRB1, TAP2/TAP1, and HLA-DPB1 haplotypes in Finnish juvenile idiopathic arthritis: more complexity within the MHC.
|
15343265 |
2004 |
HLA-DPB1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Juvenile idiopathic arthritis (JIA) is associated with particular alleles at 3 different HLA loci: HLA-A, HLA-DR/DQ, and HLA-DP.
|
12115193 |
2002 |
HLA-DPB1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
JIA is associated with particular alleles at, at least, three different HLA loci: HLA-A (HLA-A*0201), -DR/DQ (DRB1*08, DRB1*11, DRB1*13) and -DP (DPB1*0201, DPB1*0301), with marked differences between the disease subtypes.
|
12195624 |
2002 |
HLA-DPB1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The DPB1*0201 allele was associated with the development of either EOO-JCA or CAU.
|
10457895 |
1999 |
HLA-DPB1
|
0.100 |
Biomarker
|
disease |
BEFREE |
Interaction between HLA-DR and HLA-DP, and between HLA and interleukin 1 alpha in juvenile rheumatoid arthritis indicates heterogeneity of pathogenic mechanisms of the disease.
|
7558921 |
1995 |
HLA-DPB1
|
0.100 |
Biomarker
|
disease |
BEFREE |
Stratification of the EOPA-JCA group into antinuclear antibody (ANA) positive (n = 18) and ANA negative (n = 25) individuals revealed that ANA positivity was only associated with DRB1*1301 (OR 4.2, 95% CI 1.0-17.3), DPB1*0201 (OR 4.0, 95% CI 1.0-15.7) and DQB1*0603 (OR 11.5, 95% CI 2.5-53.4).
|
7788177 |
1995 |
HLA-DPB1
|
0.100 |
Biomarker
|
disease |
BEFREE |
Certain HLA associations (DRB1*0801, DPB1*0201) appear to be present in patients with JA in most studies; others (DRB1*1301, DPB1*0301) are more variable.
|
8151573 |
1994 |
HLA-DPB1
|
0.100 |
Biomarker
|
disease |
BEFREE |
HLA-DP/DR interaction in early onset pauciarticular juvenile chronic arthritis.
|
8436419 |
1993 |
HLA-DPB1
|
0.100 |
Biomarker
|
disease |
BEFREE |
DNA typing for HLA-DPB1*02 and -DPB1*04 in multiple sclerosis and juvenile rheumatoid arthritis.
|
2228045 |
1990 |