Gene: EGFR ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.360 GeneticVariation disease BEFREE Overall, the presence of mutations in EGFR or in its transducers did not affect PFS or OS, while the extrahepatic cholangiocarcinoma (ECC) mutated patients had a worse prognosis compared to WT. 29352306 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.360 AlteredExpression disease BEFREE Among distal EHCC samples, 6.0% (n=5) were positive (3+) for EGFR expression and 6.0% (n=5) were equivocal (2+). 28843919 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.360 GeneticVariation disease BEFREE No simultaneous EGFR and KRAS mutations in extrahepatic cholangiocarcinoma and gallbladder carcinoma were found. 24372748 2014
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.360 AlteredExpression disease BEFREE Importantly, our findings suggested significant association of SOX4 and EGFR expression both in IHCC (P<0.001) and EHCC (P=0.014). 25181339 2014
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.360 AlteredExpression disease BEFREE EGFR, HER3 and HER4 were overexpressed in 20 (30.8%), 8 (12.3%) and 41 (63.1%) of the 65 intrahepatic cholangiocarcinomas (IHCCs), and in 23 (20.9%), 13 (11.8%) and 62 (56.4%) of the 110 extrahepatic cholangiocarcinomas (EHCCs), respectively. 24927194 2014
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.360 AlteredExpression disease BEFREE Clinicopathologically, EGFR overexpression was associated with macroscopic type (P=0.0120), lymph node metastasis (P=0.0006), tumour stage (P=0.0424), lymphatic vessel invasion (P=0.0371), and perineural invasion (P=0.0459) in EHCC, and VEGF overexpression with intrahepatic metastasis (P=0.0224) in IHCC. 18087285 2008
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.360 Therapeutic disease CTD_human Effects of the anti-epidermal growth factor receptor antibody cetuximab on cholangiocarcinoma of the liver. 17341899 2007