Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7849
Gene Symbol: PAX8
PAX8
0.040 AlteredExpression disease BEFREE We aimed to determine the effects of PAX8 expression on the migrative, adhesive and survival capabilities of high-grade serous carcinoma cells. 31832016 2019
Entrez Id: 7849
Gene Symbol: PAX8
PAX8
0.040 AlteredExpression disease BEFREE We show that PAX8 positively regulates the expression of TP53 in HGSC and the pro-proliferative role of PAX8 is mediated by the GOF activity of mutant p53. 29379162 2018
Entrez Id: 7849
Gene Symbol: PAX8
PAX8
0.040 Biomarker disease BEFREE Candidate genes and pathways downstream of PAX8 involved in ovarian high-grade serous carcinoma. 27259239 2016
Entrez Id: 7849
Gene Symbol: PAX8
PAX8
0.040 Biomarker disease BEFREE Finally, PAX8 knockdown in HGSC cell lines resulted in increased apoptosis and decreased FOXM1 levels. 27129161 2016