Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3565
Gene Symbol: IL4
IL4
0.030 Biomarker disease BEFREE The objective of the study is to demonstrate that IL-4 and INF-γ cytokines, are capable of inducing in healthy nasal mucosa (NM) the dysregulation of the autocrine loop of COX reported in AERD. 30961940 2019
Entrez Id: 3565
Gene Symbol: IL4
IL4
0.030 AlteredExpression disease BEFREE Increased levels of both interleukin-4 (IL-4) and interferon (IFN)-γ are present in the tissue of patients with AERD. 27712766 2016
Entrez Id: 3565
Gene Symbol: IL4
IL4
0.030 Biomarker disease BEFREE Our results suggest that IL-4 is an inflammatory component mediating intolerance reactions to aspirin, and thus is crucial for AERD pathogenesis. 27534531 2016