Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
0.040 GeneticVariation disease BEFREE VLBW infants carrying ≥ 2 NOD2 genetic risk factors of inflammatory bowel disease in adults have an increased risk for severe gastrointestinal complications, such as NEC requiring surgery. 26752461 2016
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
0.040 AlteredExpression disease BEFREE Strikingly, activation of NOD2 reduced SMAC-DIABLO expression, attenuated the extent of enterocyte apoptosis, and reduced the severity of NEC. 20580721 2010
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
0.040 Biomarker disease BEFREE Carrier state of the tested CD14, TLR4, and CARD15 SNPs is not associated with NEC risk in VLBW infants. 16385250 2006
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
0.040 Biomarker disease BEFREE Our results suggest that CARD15/NOD2 does not play a major role in genetic susceptibility to NEC. 16133969 2005