Disease: Cushing Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ACP5 P13686 acid phosphatase 5, tartrate resistant 7.9E-02 0.561 0.731
ARMC5 Q96C12 armadillo repeat containing 5 0.11 0.670 0.500
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BRD2 P25440 bromodomain containing 2 Epigenetic regulator 1.00 0.450 0.808
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731
COX8A P10176 cytochrome c oxidase subunit 8A Enzyme 0.12 0.400 0.846
CPA1 P15085 carboxypeptidase A1 Enzyme 2.7E-11 0.650 0.577
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CYP11B1 P15538 cytochrome P450 family 11 subfamily B member 1 8.2E-07 0.563 0.615
CYP11B2 P19099 cytochrome P450 family 11 subfamily B member 2 7.1E-19 0.553 0.615
F12 P00748 coagulation factor XII Enzyme 8.3E-08 0.612 0.577
GABRA6 Q16445 gamma-aminobutyric acid type A receptor subunit alpha6 Ion channel 1.3E-12 0.678 0.423
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
GIP P09681 gastric inhibitory polypeptide 0.27 0.570 0.654
GIPR P48546 gastric inhibitory polypeptide receptor G-protein coupled receptor 2.0E-29 0.670 0.538
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
HSD11B1 P28845 hydroxysteroid 11-beta dehydrogenase 1 0.42 0.520 0.731
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
KCNJ5 P48544 potassium inwardly rectifying channel subfamily J member 5 Ion channel 3.4E-04 0.560 0.577
KRT5 P13647 keratin 5 0.64 0.512 0.731
LEP P41159 leptin 0.46 0.349 0.846
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
PHLDA2 Q53GA4 pleckstrin homology like domain family A member 2 0.15 0.636 0.615
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846