Disease: Idiopathic pulmonary arterial hypertension
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ANG P03950 angiogenin 0.29 0.511 0.769
ANGPT1 Q15389 angiopoietin 1 Signaling 0.95 0.446 0.808
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
ATF4 P18848 activating transcription factor 4 1.6E-02 0.507 0.769
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CA9 Q16790 carbonic anhydrase 9 1.3E-09 0.483 0.731
CAPN1 P07384 calpain 1 Enzyme 5.9E-10 0.539 0.808
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CCN1 O00622 cellular communication network factor 1 Signaling 0.71 0.473 0.731
CCN2 P29279 cellular communication network factor 2 Signaling 5.0E-04 0.399 0.846
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CFTR P13569 CF transmembrane conductance regulator Ion channel 2.2E-58 0.424 0.885
CREB1 P16220 cAMP responsive element binding protein 1 1.00 0.463 0.885
CS O75390 citrate synthase Enzyme 0.98 0.590 0.654
CTBP1 Q13363 C-terminal binding protein 1 Transcription factor 0.98 0.559 0.692
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846