Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
DHCR7 | Q9UBM7 | 7-dehydrocholesterol reductase | Enzyme | 3.9E-13 | 0.500 | 0.846 |
HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
KDM6A | O15550 | lysine demethylase 6A | Epigenetic regulator | 1.00 | 0.498 | 0.769 |
KMT2D | O14686 | lysine methyltransferase 2D | 1.00 | 0.465 | 0.808 | |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
LZTR1 | Q8N653 | leucine zipper like transcription regulator 1 | 1.0E-92 | 0.547 | 0.808 | |
NRAS | P01111 | NRAS proto-oncogene, GTPase | Enzyme modulator | 0.49 | 0.390 | 0.808 |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
RAP1A | P62834 | RAP1A, member of RAS oncogene family | Enzyme modulator | 0.62 | 0.502 | 0.808 |
RAP1B | P61224 | RAP1B, member of RAS oncogene family | Enzyme modulator | 0.91 | 0.565 | 0.769 |
SOS2 | Q07890 | SOS Ras/Rho guanine nucleotide exchange factor 2 | Enzyme modulator | 1.00 | 0.608 | 0.692 |