Disease: androgen independent prostate cancer
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
TWIST1 Q15672 twist family bHLH transcription factor 1 Transcription factor 0.34 0.397 0.846
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885
HSP90AA1 P07900 heat shock protein 90 alpha family class A member 1 Chaperone 0.86 0.411 0.923
NR1I2 O75469 nuclear receptor subfamily 1 group I member 2 Nuclear receptor 7.3E-09 0.418 0.846
MCL1 Q07820 MCL1 apoptosis regulator, BCL2 family member Signaling 0.96 0.430 0.808
EGR1 P18146 early growth response 1 Nucleic acid binding 0.35 0.433 0.923
RUNX2 Q13950 RUNX family transcription factor 2 Transcription factor 0.95 0.437 0.846
JUN P05412 Jun proto-oncogene, AP-1 transcription factor subunit Transcription factor 6.0E-02 0.442 0.885
KLK3 P07288 kallikrein related peptidase 3 Enzyme 4.4E-06 0.443 0.885
ERG P11308 ETS transcription factor ERG Transcription factor 0.96 0.453 0.808
CYP17A1 P05093 cytochrome P450 family 17 subfamily A member 1 2.6E-04 0.462 0.769
FOSB P53539 FosB proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.98 0.463 0.846
MBD2 Q9UBB5 methyl-CpG binding domain protein 2 Epigenetic regulator 0.35 0.466 0.846
JUNB P17275 JunB proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.86 0.467 0.769
PROS1 P07225 protein S 4.7E-04 0.467 0.846
JUND P17535 JunD proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.70 0.475 0.808
PSAT1 Q9Y617 phosphoserine aminotransferase 1 1.1E-08 0.478 0.846
PTPA Q15257 protein phosphatase 2 phosphatase activator Enzyme modulator 0.99 0.480 0.846
PLAG1 Q6DJT9 PLAG1 zinc finger Transcription factor 1.00 0.493 0.808
AGO2 Q9UKV8 argonaute RISC catalytic component 2 1.00 0.501 0.885