Disease: Neoplastic Syndromes, Hereditary
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PART1 prostate androgen-regulated transcript 1 0.483 0.885
CDKN2B-AS1 CDKN2B antisense RNA 1 0.491 0.769
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
MUTYH Q9UIF7 mutY DNA glycosylase Enzyme 1.3E-18 0.521 0.769
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
SARDH Q9UL12 sarcosine dehydrogenase Enzyme 5.3E-16 0.523 0.846
RAD51B O15315 RAD51 paralog B 2.1E-15 0.556 0.769
MRE11 P49959 MRE11 homolog, double strand break repair nuclease 1.3E-12 0.527 0.808
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923
POLD1 P28340 DNA polymerase delta 1, catalytic subunit 2.4E-06 0.507 0.769
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
MRC1 P22897 mannose receptor C-type 1 0.94 0.413 0.846
MITF O75030 melanocyte inducing transcription factor 0.98 0.499 0.808