Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
CACNA1A O00555 calcium voltage-gated channel subunit alpha1 A Ion channel 1.00 0.489 0.769
TPO P07202 thyroid peroxidase Enzyme 1.8E-21 0.455 0.846
SNAP25 P60880 synaptosome associated protein 25 Transporter 0.99 0.489 0.808
SYNE1 Q8NF91 spectrin repeat containing nuclear envelope protein 1 3.2E-52 0.511 0.846
FGF21 Q9NSA1 fibroblast growth factor 21 Signaling 2.9E-02 0.485 0.769
FXN Q16595 frataxin Enzyme 0.34 0.510 0.654
ATXN1 P54253 ataxin 1 0.97 0.534 0.769
ATXN3 P54252 ataxin 3 Enzyme 0.11 0.521 0.808
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577
WFS1 O76024 wolframin ER transmembrane glycoprotein 1.6E-38 0.528 0.846
GRM1 Q13255 glutamate metabotropic receptor 1 G-protein coupled receptor 0.14 0.528 0.808
TBP P20226 TATA-box binding protein Transcription factor 1.5E-02 0.552 0.846
TPP1 O14773 tripeptidyl peptidase 1 Enzyme 6.3E-07 0.551 0.808
TTPA P49638 alpha tocopherol transfer protein Transporter 1.4E-03 0.612 0.577
TOP1 P11387 DNA topoisomerase I Enzyme 1.00 0.542 0.692
HSD17B4 P51659 hydroxysteroid 17-beta dehydrogenase 4 2.4E-10 0.546 0.654
SETX Q7Z333 senataxin Enzyme 0.95 0.570 0.731
AFG3L2 Q9Y4W6 AFG3 like matrix AAA peptidase subunit 2 Enzyme 5.3E-09 0.588 0.462