Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
DMD P11532 dystrophin 1.00 0.423 0.923
SETD2 Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 1.00 0.424 0.846
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808
TSC2 P49815 TSC complex subunit 2 Enzyme modulator 1.00 0.439 0.808
TSC1 Q92574 TSC complex subunit 1 1.00 0.440 0.808
EHMT1 Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 1.00 0.460 0.808
SMARCA4 P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 1.00 0.450 0.885
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769
CACNA1A O00555 calcium voltage-gated channel subunit alpha1 A Ion channel 1.00 0.489 0.769
PRKCB P05771 protein kinase C beta Kinase 1.00 0.453 0.885
FLT4 P35916 fms related receptor tyrosine kinase 4 Kinase 1.00 0.457 0.808
SCN8A Q9UQD0 sodium voltage-gated channel alpha subunit 8 Ion channel 1.00 0.510 0.731