Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
ELN P15502 elastin 2.1E-14 0.415 0.885
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
CALCA P01258 P06881 calcitonin related polypeptide alpha Signaling 1.6E-02 0.416 0.923
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
AFP P02771 alpha fetoprotein Transporter 1.1E-11 0.429 0.885
S100A8 P05109 S100 calcium binding protein A8 Calcium-binding protein 0.14 0.430 0.962
LGALS1 P09382 galectin 1 Signaling 4.5E-03 0.435 0.846
PAX6 P26367 paired box 6 1.00 0.450 0.769
POU5F1 Q01860 POU class 5 homeobox 1 0.95 0.441 0.846