Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
SMUG1 | Q53HV7 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 4.5E-04 | 0.322 | 0.923 | |
MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
TERT | O14746 | telomerase reverse transcriptase | Enzyme | 0.99 | 0.374 | 0.846 |
HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
NRAS | P01111 | NRAS proto-oncogene, GTPase | Enzyme modulator | 0.49 | 0.390 | 0.808 |
IGF2 | P01344 | insulin like growth factor 2 | 4.4E-02 | 0.390 | 0.885 | |
IGF1R | P08069 | insulin like growth factor 1 receptor | Kinase | 0.97 | 0.399 | 0.885 |
ELN | P15502 | elastin | 2.1E-14 | 0.415 | 0.885 | |
GNAS | O95467 P63092 P84996 Q5JWF2 | GNAS complex locus | Enzyme modulator | 0.68 | 0.420 | 0.885 |
PTH | P01270 | parathyroid hormone | 1.2E-02 | 0.397 | 0.846 | |
HTC2 | hypertrichosis 2 (generalized, congenital) | 0.392 | 0.808 | |||
SOX2 | P48431 | SRY-box transcription factor 2 | Transcription factor | 0.71 | 0.405 | 0.808 |
DNMT1 | P26358 | DNA methyltransferase 1 | Epigenetic regulator | 1.00 | 0.406 | 0.885 |
SMAD3 | P84022 | SMAD family member 3 | Transcription factor | 0.80 | 0.415 | 0.923 |
CALCA | P01258 P06881 | calcitonin related polypeptide alpha | Signaling | 1.6E-02 | 0.416 | 0.923 |
WT1 | P19544 | WT1 transcription factor | Nucleic acid binding | 1.00 | 0.422 | 0.808 |
AFP | P02771 | alpha fetoprotein | Transporter | 1.1E-11 | 0.429 | 0.885 |
S100A8 | P05109 | S100 calcium binding protein A8 | Calcium-binding protein | 0.14 | 0.430 | 0.962 |
LGALS1 | P09382 | galectin 1 | Signaling | 4.5E-03 | 0.435 | 0.846 |
PAX6 | P26367 | paired box 6 | 1.00 | 0.450 | 0.769 | |
POU5F1 | Q01860 | POU class 5 homeobox 1 | 0.95 | 0.441 | 0.846 |