Disease: MAJOR AFFECTIVE DISORDER 2
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ANK3 Q12955 ankyrin 3 1.00 0.578 0.654
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BPI P17213 bactericidal permeability increasing protein 1.7E-14 0.610 0.769
BRD1 O95696 bromodomain containing 1 1.00 0.644 0.654
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846
CHRNA7 P36544 Q494W8 cholinergic receptor nicotinic alpha 7 subunit Ion channel 4.2E-04 0.532 0.654
CLOCK O15516 clock circadian regulator 1.00 0.463 0.885
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
DDC P20711 dopa decarboxylase 3.8E-08 0.535 0.769
DGKH Q86XP1 diacylglycerol kinase eta Kinase 2.6E-02 0.678 0.346
DISC1 Q9NRI5 DISC1 scaffold protein 1.7E-06 0.548 0.769
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846
F2R P25116 coagulation factor II thrombin receptor G-protein coupled receptor 8.5E-03 0.444 0.846
GAD1 Q99259 glutamate decarboxylase 1 Enzyme 4.6E-02 0.486 0.885
GRK3 P35626 G protein-coupled receptor kinase 3 Kinase 0.71 0.621 0.731
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
HTR2C P28335 5-hydroxytryptamine receptor 2C G-protein coupled receptor 3.7E-02 0.555 0.692
HTR3A P46098 5-hydroxytryptamine receptor 3A Ion channel 1.7E-10 0.608 0.538
IGFBP2 P18065 insulin like growth factor binding protein 2 Enzyme modulator 0.12 0.478 0.769