Disease: NEUROTICISM
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ARR3 P36575 arrestin 3 Enzyme modulator 0.10 0.460 0.846
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CASR P41180 calcium sensing receptor G-protein coupled receptor 4.7E-02 0.410 0.846
CHRNA7 P36544 Q494W8 cholinergic receptor nicotinic alpha 7 subunit Ion channel 4.2E-04 0.532 0.654
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CXADR P78310 CXADR Ig-like cell adhesion molecule 0.37 0.454 0.885
CXADRP1 CXADR pseudogene 1 0.463 0.846
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
FKBP5 Q13451 FKBP prolyl isomerase 5 Enzyme 0.73 0.524 0.769
GAD2 Q05329 glutamate decarboxylase 2 Enzyme 0.75 0.529 0.731
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
MCPH1 Q8NEM0 microcephalin 1 Nucleic acid binding 7.8E-30 0.540 0.846
MDD1 Major depressive disorder 0.682 0.308
MTA2 O94776 metastasis associated 1 family member 2 Nucleic acid binding 0.74 0.579 0.808
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
NR1I3 Q14994 nuclear receptor subfamily 1 group I member 3 Nuclear receptor 3.5E-08 0.448 0.846
NR3C2 P08235 nuclear receptor subfamily 3 group C member 2 Nuclear receptor 0.84 0.469 0.846
NRG1 Q02297 neuregulin 1 Signaling 1.00 0.464 0.885
OXTR P30559 oxytocin receptor G-protein coupled receptor 7.1E-04 0.541 0.769