Disease: Medulloblastoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
ABCG2 Q9UNQ0 ATP binding cassette subfamily G member 2 (Junior blood group) Transporter 2.1E-32 0.419 0.885
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
ABCC3 O15438 ATP binding cassette subfamily C member 3 Transporter 1.2E-26 0.517 0.769
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846
PROM1 O43490 prominin 1 Transporter 1.9E-22 0.410 0.846
MELK Q14680 maternal embryonic leucine zipper kinase Kinase 4.5E-22 0.566 0.577
GNL3 Q9BVP2 G protein nucleolar 3 2.0E-19 0.579 0.577
AFM P43652 afamin Transporter 4.3E-19 0.590 0.731
CYP1A1 P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 1.1E-17 0.436 0.846
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
ADAM8 P78325 ADAM metallopeptidase domain 8 Enzyme 2.2E-14 0.590 0.731
HPSE Q9Y251 heparanase Enzyme 2.3E-14 0.425 0.808
GLI1 P08151 GLI family zinc finger 1 7.7E-14 0.431 0.846
SSTR4 P31391 somatostatin receptor 4 G-protein coupled receptor 3.7E-13 0.469 0.846
IDUA P35475 alpha-L-iduronidase Enzyme 3.8E-13 0.499 0.846
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
NT5E P21589 5'-nucleotidase ecto Enzyme 2.3E-11 0.436 0.885
SLCO6A1 Q86UG4 solute carrier organic anion transporter family member 6A1 Transporter 2.9E-11 0.412 0.885