Disease: Achondroplasia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SNAI1 O95863 snail family transcriptional repressor 1 0.22 0.474 0.808
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
FGF1 P05230 fibroblast growth factor 1 Signaling 0.44 0.507 0.846
DCN P07585 decorin 0.31 0.457 0.808
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
CNP P09543 2',3'-cyclic nucleotide 3' phosphodiesterase Enzyme 0.98 0.604 0.692
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
PTHLH P12272 parathyroid hormone like hormone 0.81 0.453 0.846
EDN3 P14138 endothelin 3 Signaling 2.5E-02 0.608 0.577
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
POU1F1 P28069 POU class 1 homeobox 1 4.5E-02 0.548 0.654
MSX1 P28360 msh homeobox 1 Transcription factor 0.17 0.525 0.731
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
CYP2C19 P33261 cytochrome P450 family 2 subfamily C member 19 6.5E-20 0.467 0.846
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808