Disease: Acanthosis Nigricans
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
JUP P14923 junction plakoglobin 8.0E-04 0.628 0.500
LIPE Q05469 lipase E, hormone sensitive type 9.7E-12 0.599 0.500
PRMT7 Q9NVM4 protein arginine methyltransferase 7 Epigenetic regulator 5.5E-15 0.674 0.538
PCSK1 P29120 proprotein convertase subtilisin/kexin type 1 Enzyme 2.7E-09 0.548 0.615
PSMB4 P28070 proteasome 20S subunit beta 4 2.6E-03 0.659 0.615
NSMCE2 Q96MF7 NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase 3.8E-02 0.682 0.615
CAVIN1 Q6NZI2 caveolae associated protein 1 Transcription factor 5.0E-03 0.559 0.654
KRT18 P05783 keratin 18 0.73 0.530 0.692
MC4R P32245 melanocortin 4 receptor G-protein coupled receptor 9.2E-04 0.535 0.692
ZMPSTE24 O75844 zinc metallopeptidase STE24 Enzyme 8.9E-16 0.517 0.731
AKT2 P31751 AKT serine/threonine kinase 2 Kinase 0.64 0.474 0.769
XRCC4 Q13426 X-ray repair cross complementing 4 8.3E-07 0.528 0.769
CUL4B Q13620 cullin 4B Enzyme 1.00 0.556 0.769
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
GZMB P10144 granzyme B Enzyme 3.7E-14 0.453 0.808
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
PSMB9 P28065 proteasome 20S subunit beta 9 2.7E-03 0.514 0.808
CLDN1 O95832 claudin 1 Cell-cell junction 1.0E-03 0.481 0.808
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
LEP P41159 leptin 0.46 0.349 0.846
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
SERPINF1 P36955 serpin family F member 1 Enzyme modulator 7.8E-08 0.460 0.846
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
PNPLA2 Q96AD5 patatin like phospholipase domain containing 2 Enzyme 4.1E-03 0.511 0.846