Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
U2AF1 | P0DN76 Q01081 | U2 small nuclear RNA auxiliary factor 1 | Nucleic acid binding | 0.99 | 0.604 | 0.577 |
CREBBP | Q92793 | CREB binding protein | 1.00 | 0.428 | 0.808 | |
FBXW7 | Q969H0 | F-box and WD repeat domain containing 7 | Enzyme modulator | 1.00 | 0.465 | 0.808 |
SMAD4 | Q13485 | SMAD family member 4 | Transcription factor | 1.00 | 0.401 | 0.808 |
ERBB3 | P21860 | erb-b2 receptor tyrosine kinase 3 | Kinase | 1.7E-15 | 0.448 | 0.808 |
EP300 | Q09472 | E1A binding protein p300 | 1.00 | 0.459 | 0.846 | |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
GNAS | O95467 P63092 P84996 Q5JWF2 | GNAS complex locus | Enzyme modulator | 0.68 | 0.420 | 0.885 |
NFE2L2 | Q16236 | nuclear factor, erythroid 2 like 2 | Enzyme | 3.6E-03 | 0.357 | 0.885 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
MAPK1 | P28482 | mitogen-activated protein kinase 1 | Kinase | 1.00 | 0.330 | 0.923 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |