Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ATXN2 | Q99700 | ataxin 2 | Nucleic acid binding | 0.85 | 0.482 | 0.808 |
HLA-DRB1 | P01911 | major histocompatibility complex, class II, DR beta 1 | Immune response | 1.1E-03 | 0.333 | 0.923 |
PTPN22 | Q9Y2R2 | protein tyrosine phosphatase non-receptor type 22 | 3.5E-21 | 0.438 | 0.846 | |
TCF4 | P15884 | transcription factor 4 | Transcription factor | 1.00 | 0.464 | 0.846 |
IFIH1 | Q9BYX4 | interferon induced with helicase C domain 1 | 7.0E-44 | 0.471 | 0.808 | |
STAT4 | Q14765 | signal transducer and activator of transcription 4 | Nucleic acid binding | 0.77 | 0.471 | 0.769 |
SMAD3 | P84022 | SMAD family member 3 | Transcription factor | 0.80 | 0.415 | 0.923 |
STAT3 | P40763 | signal transducer and activator of transcription 3 | Nucleic acid binding | 1.00 | 0.320 | 0.923 |
SH2B3 | Q9UQQ2 | SH2B adaptor protein 3 | 1.0E-04 | 0.527 | 0.692 | |
TET2 | Q6N021 | tet methylcytosine dioxygenase 2 | 4.3E-54 | 0.458 | 0.808 | |
RTEL1 | Q9NZ71 | regulator of telomere elongation helicase 1 | Enzyme | 8.9E-10 | 0.459 | 0.808 |
IL23R | Q5VWK5 | interleukin 23 receptor | Signaling | 5.6E-04 | 0.466 | 0.769 |
DAG1 | Q14118 | dystroglycan 1 | Receptor | 0.98 | 0.498 | 0.808 |
ERAP1 | Q9NZ08 | endoplasmic reticulum aminopeptidase 1 | Enzyme | 2.1E-26 | 0.556 | 0.692 |
CYP21A2 | P08686 | cytochrome P450 family 21 subfamily A member 2 | 2.6E-04 | 0.525 | 0.769 | |
IL10 | P22301 | interleukin 10 | 5.9E-03 | 0.281 | 0.923 | |
GCKR | Q14397 | glucokinase regulator | 8.5E-19 | 0.604 | 0.615 | |
UBAC2 | Q8NBM4 | UBA domain containing 2 | 6.3E-03 | 0.638 | 0.654 | |
TLR4 | O00206 | toll like receptor 4 | 4.6E-09 | 0.321 | 0.962 | |
HLA-DQA1 | P01909 | major histocompatibility complex, class II, DQ alpha 1 | Immune response | 2.4E-02 | 0.416 | 0.846 |
NOTCH1 | P46531 | notch receptor 1 | 1.00 | 0.369 | 0.885 | |
DNMT3A | Q9Y6K1 | DNA methyltransferase 3 alpha | 7.4E-39 | 0.445 | 0.846 | |
NOD2 | Q9HC29 | nucleotide binding oligomerization domain containing 2 | Enzyme | 2.0E-30 | 0.423 | 0.923 |
LRRK2 | Q5S007 | leucine rich repeat kinase 2 | Kinase | 2.6E-30 | 0.510 | 0.808 |
CRB1 | P82279 | crumbs cell polarity complex component 1 | 5.6E-16 | 0.570 | 0.654 |