Disease: Gait Ataxia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
ATN1 P54259 atrophin 1 1.00 0.409 0.885
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
DKK1 O94907 dickkopf WNT signaling pathway inhibitor 1 0.17 0.439 0.885
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
NUP62 P37198 nucleoporin 62 Transporter 0.95 0.470 0.885
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
SLC52A2 Q9HAB3 solute carrier family 52 member 2 Transporter 2.5E-03 0.483 0.808
CACNA1A O00555 calcium voltage-gated channel subunit alpha1 A Ion channel 1.00 0.489 0.769
ADAR P55265 adenosine deaminase RNA specific Enzyme 2.6E-02 0.501 0.808
MPZ P25189 myelin protein zero 0.27 0.503 0.846
FXN Q16595 frataxin Enzyme 0.34 0.510 0.654
GCH1 P30793 GTP cyclohydrolase 1 Enzyme 0.90 0.511 0.846
SLC9A6 Q92581 solute carrier family 9 member A6 Transporter 1.00 0.516 0.846
TWNK Q96RR1 twinkle mtDNA helicase Enzyme 3.2E-03 0.516 0.692
ATXN3 P54252 ataxin 3 Enzyme 0.11 0.521 0.808
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769
MRE11 P49959 MRE11 homolog, double strand break repair nuclease 1.3E-12 0.527 0.808
RRM2B Q7LG56 ribonucleotide reductase regulatory TP53 inducible subunit M2B Enzyme 2.4E-03 0.527 0.769
GRM1 Q13255 glutamate metabotropic receptor 1 G-protein coupled receptor 0.14 0.528 0.808