Disease: Neuromyelitis Optica
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCG2 Q9UNQ0 ATP binding cassette subfamily G member 2 (Junior blood group) Transporter 2.1E-32 0.419 0.885
AQP4 P55087 aquaporin 4 Ion channel 2.3E-03 0.456 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CD59 P13987 CD59 molecule (CD59 blood group) 0.61 0.469 0.808
CISH Q9NSE2 cytokine inducible SH2 containing protein Enzyme modulator 5.4E-04 0.500 0.808
CXCR2 P25025 C-X-C motif chemokine receptor 2 G-protein coupled receptor 1.4E-02 0.445 0.923
EPO P01588 erythropoietin 1.1E-02 0.381 0.885
FCRL3 Q96P31 Fc receptor like 3 Cell adhesion 6.0E-21 0.612 0.769
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
GPC5 P78333 glypican 5 4.0E-10 0.626 0.654
HLA-DPA1 P20036 major histocompatibility complex, class II, DP alpha 1 Immune response 2.5E-06 0.552 0.846
HLA-DPB1 P04440 major histocompatibility complex, class II, DP beta 1 Immune response 5.3E-10 0.453 0.923
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
IFNB1 P01574 interferon beta 1 0.421 0.846
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
IL7R P16871 interleukin 7 receptor Receptor 3.8E-07 0.487 0.769
IRF8 Q02556 interferon regulatory factor 8 Transcription factor 0.95 0.539 0.808
MBP P02686 myelin basic protein 0.28 0.510 0.885
MOG Q16653 myelin oligodendrocyte glycoprotein Enzyme modulator 0.14 0.546 0.731
MS multiple sclerosis 0.599 0.692