Disease: Ichthyoses
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCA12 Q86UK0 ATP binding cassette subfamily A member 12 Transporter 2.9E-15 0.610 0.654
ABHD5 Q8WTS1 abhydrolase domain containing 5 6.4E-07 0.641 0.538
ALOX12B O75342 arachidonate 12-lipoxygenase, 12R type Enzyme 7.6E-04 0.603 0.577
ALOXE3 Q9BYJ1 arachidonate lipoxygenase 3 Enzyme 5.1E-20 0.644 0.538
CARD14 Q9BXL6 caspase recruitment domain family member 14 1.2E-19 0.546 0.846
CERS3 Q8IU89 ceramide synthase 3 5.7E-03 0.705 0.308
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846
CYP4F22 Q6NT55 cytochrome P450 family 4 subfamily F member 22 Enzyme 5.3E-06 0.705 0.462
DSP P15924 desmoplakin Cellular structure 1.00 0.514 0.808
EBP Q15125 EBP cholestenol delta-isomerase Enzyme 0.94 0.494 0.846
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
GJB2 P29033 gap junction protein beta 2 Cell-cell junction 6.6E-16 0.441 0.846
GTF2H5 Q6ZYL4 general transcription factor IIH subunit 5 4.5E-02 0.556 0.769
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
IL17F Q96PD4 interleukin 17F 3.9E-02 0.480 0.808
KRT1 P04264 keratin 1 0.74 0.575 0.654
KRT10 P13645 keratin 10 2.5E-03 0.579 0.692
LIPN Q5VXI9 lipase family member N 3.1E-05 0.736 0.423
MBTPS2 O43462 membrane bound transcription factor peptidase, site 2 Enzyme 1.00 0.513 0.769
MPDU1 O75352 mannose-P-dolichol utilization defect 1 1.0E-05 0.682 0.500
NIPAL4 Q0D2K0 NIPA like domain containing 4 1.4E-03 0.682 0.423
PNPLA1 Q8N8W4 patatin like phospholipase domain containing 1 Enzyme 1.9E-04 0.700 0.423
SDR9C7 Q8NEX9 short chain dehydrogenase/reductase family 9C member 7 Enzyme 1.2E-02 0.695 0.538
SPINK5 Q9NQ38 serine peptidase inhibitor Kazal type 5 Enzyme modulator 4.8E-28 0.604 0.654
SULT2B1 O00204 sulfotransferase family 2B member 1 0.44 0.641 0.538