Disease: Hyperhomocysteinemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808