| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| ACHE | P22303 | acetylcholinesterase (Cartwright blood group) | Enzyme | 1.00 | 0.445 | 0.885 |
| CHRNA3 | P32297 | cholinergic receptor nicotinic alpha 3 subunit | Ion channel | 1.4E-07 | 0.588 | 0.692 |
| CHRNA4 | P43681 | cholinergic receptor nicotinic alpha 4 subunit | Ion channel | 8.5E-05 | 0.492 | 0.808 |
| CHRNA6 | Q15825 | cholinergic receptor nicotinic alpha 6 subunit | Ion channel | 3.6E-08 | 0.711 | 0.346 |
| CHRNA7 | P36544 Q494W8 | cholinergic receptor nicotinic alpha 7 subunit | Ion channel | 4.2E-04 | 0.532 | 0.654 |
| CHRNB2 | P17787 | cholinergic receptor nicotinic beta 2 subunit | Ion channel | 7.3E-04 | 0.617 | 0.308 |
| CHRNB3 | Q05901 | cholinergic receptor nicotinic beta 3 subunit | Ion channel | 8.6E-06 | 0.705 | 0.308 |
| CHRNB4 | P30926 | cholinergic receptor nicotinic beta 4 subunit | Ion channel | 0.14 | 0.644 | 0.423 |
| COMT | P21964 | catechol-O-methyltransferase | Enzyme | 1.1E-06 | 0.400 | 0.923 |
| COPD | Pulmonary disease, chronic obstructive, severe early-onset | 0.456 | 0.885 | |||
| CYP3A5 | P20815 | cytochrome P450 family 3 subfamily A member 5 | Enzyme | 6.3E-17 | 0.511 | 0.846 |
| GRM5 | P41594 | glutamate metabotropic receptor 5 | G-protein coupled receptor | 1.00 | 0.525 | 0.846 |
| HINT1 | P49773 | histidine triad nucleotide binding protein 1 | Enzyme | 1.8E-03 | 0.619 | 0.577 |
| IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
| OPRM1 | P35372 | opioid receptor mu 1 | G-protein coupled receptor | 7.9E-11 | 0.457 | 0.808 |