Disease: Acidosis, Lactic
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VARS2 Q5ST30 valyl-tRNA synthetase 2, mitochondrial 5.8E-17 0.666 0.577
UQCC2 Q9BRT2 ubiquinol-cytochrome c reductase complex assembly factor 2 1.9E-02 0.705 0.462
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TRNK tRNA 0.608 0.577
TIMM50 Q3ZCQ8 translocase of inner mitochondrial membrane 50 1.8E-03 0.678 0.500
TK2 O00142 thymidine kinase 2 Kinase 3.9E-07 0.585 0.615
SUCLA2 Q9P2R7 succinate-CoA ligase ADP-forming subunit beta Enzyme 2.3E-03 0.566 0.654
SLC5A2 P31639 solute carrier family 5 member 2 Transporter 4.9E-14 0.499 0.769
PDP1 Q9P0J1 pyruvate dehyrogenase phosphatase catalytic subunit 1 Enzyme 0.45 0.691 0.462
PDHA1 P08559 pyruvate dehydrogenase E1 subunit alpha 1 0.99 0.581 0.538
PTGS1 P23219 prostaglandin-endoperoxide synthase 1 Enzyme 6.2E-07 0.460 0.885
PLAT P00750 plasminogen activator, tissue type Enzyme 5.7E-05 0.445 0.885
FARS2 O95363 phenylalanyl-tRNA synthetase 2, mitochondrial Enzyme 9.3E-09 0.615 0.731
ND6 P03923 NADH dehydrogenase, subunit 6 (complex I) 0.544 0.808
LIAS O43766 lipoic acid synthetase 2.3E-05 0.695 0.538
IL6 P05231 interleukin 6 0.32 0.248 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
GFER P55789 growth factor, augmenter of liver regeneration Enzyme 1.7E-04 0.560 0.846
EARS2 Q5JPH6 glutamyl-tRNA synthetase 2, mitochondrial Enzyme 1.1E-08 0.666 0.538
FOXRED1 Q96CU9 FAD dependent oxidoreductase domain containing 1 Enzyme 2.0E-16 0.633 0.462
DNM1L O00429 dynamin 1 like Enzyme modulator 5.7E-04 0.475 0.808
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
COX1 P00395 cytochrome c oxidase subunit I Enzyme 0.441 0.885
COX8A P10176 cytochrome c oxidase subunit 8A Enzyme 0.12 0.400 0.846