Source: CLINVAR ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
FANCM Q8IYD8 FA complementation group M Enzyme 2.4E-15 0.543 0.731
FANCC Q00597 FA complementation group C 2.8E-13 0.507 0.808
FANCI Q9NVI1 FA complementation group I 8.9E-37 0.543 0.731
SLX4 Q8IY92 SLX4 structure-specific endonuclease subunit 1.6E-22 0.565 0.731
FANCA O15360 FA complementation group A 1.6E-68 0.505 0.731
ZNF276 Q8N554 zinc finger protein 276 Transcription factor 7.9E-06 0.861 0.192
FANCG O15287 FA complementation group G 2.5E-14 0.556 0.769
FANCL Q9NW38 FA complementation group L Enzyme 5.9E-23 0.551 0.731
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
FANCF Q9NPI8 FA complementation group F 0.46 0.535 0.731
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769
GAS2 O43903 growth arrest specific 2 8.0E-04 0.792 0.269