Disease: Ichthyosis, X-Linked
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
ATF1 P18846 activating transcription factor 1 0.63 0.588 0.577
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
CD47 Q08722 CD47 molecule 0.92 0.468 0.769
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
DMD P11532 dystrophin 1.00 0.423 0.923
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
EWSR1 Q01844 EWS RNA binding protein 1 Nucleic acid binding 1.00 0.474 0.692
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
KRT20 P35900 keratin 20 9.1E-11 0.388 0.846
LGALS1 P09382 galectin 1 Signaling 4.5E-03 0.435 0.846
LGR5 O75473 leucine rich repeat containing G protein-coupled receptor 5 G-protein coupled receptor 2.5E-08 0.542 0.654
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
PDCD1 Q15116 programmed cell death 1 0.42 0.402 0.846
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
PEBP1 P30086 phosphatidylethanolamine binding protein 1 Enzyme modulator 9.2E-02 0.500 0.808