Disease: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ALB P02768 albumin Transporter 0.64 0.317 0.962
C5AR1 P21730 complement C5a receptor 1 G-protein coupled receptor 0.40 0.513 0.808
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
IGAN1 IgA nephropathy 0.524 0.808
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
KRT20 P35900 keratin 20 9.1E-11 0.388 0.846
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
MS4A1 P11836 membrane spanning 4-domains A1 Receptor 5.1E-05 0.411 0.846
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923
RBM45 Q8IUH3 RNA binding motif protein 45 2.1E-10 0.383 0.846
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TGFB2 P61812 transforming growth factor beta 2 Signaling 1.00 0.433 0.885
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TLR9 Q9NR96 toll like receptor 9 9.8E-06 0.411 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TNFSF13B Q9Y275 TNF superfamily member 13b 0.98 0.460 0.731
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923