Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
MAP2K1 Q02750 mitogen-activated protein kinase kinase 1 Kinase 0.90 0.439 0.846
ENG P17813 endoglin 1.00 0.446 0.846
SDHD O14521 succinate dehydrogenase complex subunit D Transporter 0.34 0.472 0.885
RYR1 P21817 ryanodine receptor 1 Ion channel 1.6E-29 0.489 0.808
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 2.4E-04 0.474 0.846
TEK Q02763 TEK receptor tyrosine kinase Kinase 1.00 0.462 0.692
BTK Q06187 Bruton tyrosine kinase Kinase 1.00 0.464 0.808
HOXD13 P35453 homeobox D13 8.6E-03 0.483 0.808
ACVRL1 P37023 activin A receptor like type 1 Kinase 9.7E-04 0.493 0.769
SDHC Q99643 succinate dehydrogenase complex subunit C 2.0E-04 0.517 0.846
KRIT1 O00522 KRIT1 ankyrin repeat containing 6.9E-04 0.500 0.808
DNM2 P50570 dynamin 2 Enzyme modulator 1.00 0.542 0.769
MAP2K2 P36507 mitogen-activated protein kinase kinase 2 Kinase 0.97 0.534 0.731
BIN1 O00499 bridging integrator 1 0.78 0.550 0.692