Disease: Acanthosis Nigricans
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
LIPE Q05469 lipase E, hormone sensitive type 9.7E-12 0.599 0.500
PLIN1 O60240 perilipin 1 3.1E-11 0.590 0.654
CAVIN1 Q6NZI2 caveolae associated protein 1 Transcription factor 5.0E-03 0.559 0.654
KRT18 P05783 keratin 18 0.73 0.530 0.692
AKT2 P31751 AKT serine/threonine kinase 2 Kinase 0.64 0.474 0.769
GZMB P10144 granzyme B Enzyme 3.7E-14 0.453 0.808
CLDN1 O95832 claudin 1 Cell-cell junction 1.0E-03 0.481 0.808
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
LEP P41159 leptin 0.46 0.349 0.846
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
TGFA P01135 transforming growth factor alpha Signaling 0.72 0.432 0.885
CRK P46108 CRK proto-oncogene, adaptor protein 0.96 0.394 0.923
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
AIMP2 Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 8.0E-03 0.393 0.923
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
AHSA1 O95433 activator of HSP90 ATPase activity 1 1.00 0.396 0.923
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
POLDIP2 Q9Y2S7 DNA polymerase delta interacting protein 2 0.41 0.396 0.923