Disease: Creutzfeldt-Jakob Disease, Sporadic
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PLCXD3 Q63HM9 phosphatidylinositol specific phospholipase C X domain containing 3 8.9E-03 0.861 0.154
SPRN Q5BIV9 shadow of prion protein 0.29 0.839 0.154
PRND Q9UKY0 prion like protein doppel 1.3E-02 0.751 0.192
HECTD2 Q5U5R9 HECT domain E3 ubiquitin protein ligase 2 1.00 0.805 0.231
YWHAH Q04917 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta Chaperone 0.78 0.743 0.269
STMN2 Q93045 stathmin 2 0.98 0.674 0.500
MDH1 P40925 malate dehydrogenase 1 Enzyme 0.93 0.682 0.538
ZBTB38 Q8NAP3 zinc finger and BTB domain containing 38 Transcription factor 1.00 0.663 0.615
CRYAB P02511 crystallin alpha B 2.2E-02 0.515 0.731
GPI P06744 glucose-6-phosphate isomerase Enzyme 2.8E-06 0.491 0.769
NEFL P07196 neurofilament light 0.488 0.769
RASA2 Q15283 RAS p21 protein activator 2 Enzyme modulator 7.4E-31 0.579 0.769
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769
AIF1 P55008 allograft inflammatory factor 1 Calcium-binding protein 1.9E-06 0.521 0.808
MUL1 Q969V5 mitochondrial E3 ubiquitin protein ligase 1 1.9E-06 0.473 0.808
CBLL2 Q8N7E2 Cbl proto-oncogene like 2 Enzyme 0.476 0.808
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
C4BPA P04003 complement component 4 binding protein alpha 0.46 0.556 0.846
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
ENO2 P09104 enolase 2 Enzyme 0.38 0.475 0.846
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
RARB P10826 retinoic acid receptor beta Nuclear receptor 1.00 0.478 0.846
CARD14 Q9BXL6 caspase recruitment domain family member 14 1.2E-19 0.546 0.846
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
AQP1 P29972 aquaporin 1 (Colton blood group) Ion channel 2.6E-07 0.467 0.885