Disease: Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
IFNG P01579 interferon gamma 0.47 0.288 0.962
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
S100A8 P05109 S100 calcium binding protein A8 Calcium-binding protein 0.14 0.430 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
HSP90AA1 P07900 heat shock protein 90 alpha family class A member 1 Chaperone 0.86 0.411 0.923
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923