Disease: Hairy Cell Leukemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
BTK Q06187 Bruton tyrosine kinase Kinase 1.00 0.464 0.808
CD19 P15391 CD19 molecule 0.90 0.430 0.885
CD22 P20273 CD22 molecule 0.80 0.556 0.615
CD79B P40259 CD79b molecule Receptor 0.92 0.576 0.577
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
PAX5 Q02548 paired box 5 1.00 0.487 0.654
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TRBV20OR9-2 T cell receptor beta variable 20/OR9-2 (non-functional) 0.403 0.923