Disease: Leigh Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADAR P55265 adenosine deaminase RNA specific Enzyme 2.6E-02 0.501 0.808
ATP5F1E P56381 ATP synthase F1 subunit epsilon Transporter 8.9E-03 0.686 0.500
ATN1 P54259 atrophin 1 1.00 0.409 0.885
CDSN Q15517 corneodesmosin 0.46 0.585 0.731
COX10 Q12887 cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 Enzyme 8.4E-02 0.623 0.654
COX15 Q7KZN9 cytochrome c oxidase assembly homolog COX15 1.1E-13 0.638 0.538
ECHS1 P30084 enoyl-CoA hydratase, short chain 1 Enzyme 8.8E-04 0.601 0.654
FOXRED1 Q96CU9 FAD dependent oxidoreductase domain containing 1 Enzyme 2.0E-16 0.633 0.462
LIPT1 Q9Y234 lipoyltransferase 1 Enzyme 3.8E-08 0.674 0.462
LINC01672 long intergenic non-protein coding RNA 1672 0.462 0.846
MTFMT Q96DP5 mitochondrial methionyl-tRNA formyltransferase Enzyme 1.5E-07 0.595 0.808
ND2 P03891 MTND2 0.601 0.615
ND1 P03886 NADH dehydrogenase, subunit 1 (complex I) Enzyme 0.522 0.769
ND3 P03897 NADH dehydrogenase, subunit 3 (complex I) 0.604 0.654
NDUFAF2 Q8N183 NADH:ubiquinone oxidoreductase complex assembly factor 2 2.1E-06 0.641 0.577
NDUFAF3 Q9BU61 NADH:ubiquinone oxidoreductase complex assembly factor 3 5.3E-03 0.650 0.577
NDUFAF4 Q9P032 NADH:ubiquinone oxidoreductase complex assembly factor 4 0.55 0.686 0.385
NDUFAF5 Q5TEU4 NADH:ubiquinone oxidoreductase complex assembly factor 5 3.1E-10 0.674 0.462
NDUFAF6 Q330K2 NADH:ubiquinone oxidoreductase complex assembly factor 6 9.1E-08 0.659 0.615
NDUFS1 P28331 NADH:ubiquinone oxidoreductase core subunit S1 Enzyme 6.6E-11 0.595 0.692
NDUFS2 O75306 NADH:ubiquinone oxidoreductase core subunit S2 Enzyme 1.4E-03 0.601 0.654
NDUFS3 O75489 NADH:ubiquinone oxidoreductase core subunit S3 5.8E-04 0.581 0.769
NDUFS7 O75251 NADH:ubiquinone oxidoreductase core subunit S7 0.91 0.579 0.769
NDUFS8 O00217 NADH:ubiquinone oxidoreductase core subunit S8 Enzyme 0.17 0.636 0.538
NDUFV1 P49821 NADH:ubiquinone oxidoreductase core subunit V1 6.4E-11 0.617 0.538