Disease: Midface retrusion
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BMP4 P12644 bone morphogenetic protein 4 Signaling 0.96 0.422 0.808
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CDC42 P60953 cell division cycle 42 Enzyme modulator 0.79 0.458 0.846
CDH11 P55287 cadherin 11 1.00 0.512 0.808
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
DCHS1 Q96JQ0 dachsous cadherin-related 1 1.00 0.592 0.731
DLX4 Q92988 distal-less homeobox 4 Transcription factor 1.7E-02 0.585 0.654
DVL1 O14640 dishevelled segment polarity protein 1 Signaling 3.7E-06 0.531 0.769
ELN P15502 elastin 2.1E-14 0.415 0.885
FAT4 Q6V0I7 FAT atypical cadherin 4 1.00 0.539 0.808
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
FLNA P21333 filamin A 1.00 0.419 0.846
GLI2 P10070 GLI family zinc finger 2 0.97 0.446 0.846
GPC4 O75487 glypican 4 0.93 0.547 0.769
HDAC4 P56524 histone deacetylase 4 Epigenetic regulator 1.00 0.484 0.885
KAT6B Q8WYB5 lysine acetyltransferase 6B Enzyme 1.00 0.525 0.731
MLXIPL Q9NP71 MLX interacting protein like 4.8E-02 0.554 0.731
NECTIN1 Q15223 nectin cell adhesion molecule 1 6.1E-02 0.523 0.808
OBSL1 O75147 obscurin like cytoskeletal adaptor 1 1.0E-25 0.686 0.308
PIK3R1 P27986 phosphoinositide-3-kinase regulatory subunit 1 Kinase 1.00 0.477 0.885
PITX2 Q99697 paired like homeodomain 2 0.98 0.489 0.808
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923