Disease: Dissection of aorta
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACTA2 P62736 actin alpha 2, smooth muscle Cellular structure 0.93 0.508 0.846
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
ANGPT2 O15123 angiopoietin 2 Signaling 0.83 0.410 0.846
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
COL3A1 P02461 collagen type III alpha 1 chain 1.00 0.477 0.808
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
ELN P15502 elastin 2.1E-14 0.415 0.885
FBLN5 Q9UBX5 fibulin 5 Calcium-binding protein 1.00 0.546 0.692
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
LOX P28300 lysyl oxidase 0.99 0.447 0.846
MAP2K7 O14733 mitogen-activated protein kinase kinase 7 Kinase 1.00 0.419 0.808
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
MMP12 P39900 matrix metallopeptidase 12 Enzyme 0.484 0.885
MMP14 P50281 matrix metallopeptidase 14 Enzyme 1.00 0.447 0.769
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
SMAD2 Q15796 SMAD family member 2 Transcription factor 1.00 0.456 0.808
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
TAGLN Q01995 transgelin Cellular structure 8.5E-02 0.540 0.692
TGFBR1 P36897 transforming growth factor beta receptor 1 Kinase 0.85 0.451 0.885