Disease: Von Hippel-Lindau Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CA9 Q16790 carbonic anhydrase 9 1.3E-09 0.483 0.731
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CDC73 Q6P1J9 cell division cycle 73 1.00 0.543 0.615
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
CDK6 Q00534 cyclin dependent kinase 6 Kinase 0.98 0.471 0.731
CDKN1A P38936 cyclin dependent kinase inhibitor 1A 1.9E-03 0.403 0.769
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
CHGA P10645 chromogranin A 3.0E-02 0.490 0.808
CIB1 Q99828 calcium and integrin binding 1 3.3E-04 0.458 0.769
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
GCG P01275 glucagon 3.5E-02 0.431 0.885
GNA12 Q03113 G protein subunit alpha 12 Enzyme modulator 0.97 0.547 0.769
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
HPT hypoparathyroidism 0.593 0.692
HTC2 hypertrichosis 2 (generalized, congenital) 0.392 0.808
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
MEN1 O00255 menin 1 1.00 0.444 0.808
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885